Medical Policy

Policy Num:       M5.001.006
Policy Name:     CSF Hematopoietic Colony Stimulating Factors
Policy ID:          [M5.001.006] [Ac / MA / M+ / P+] [PI]

Last Review: May 10, 2024
Next Review: May 20, 2025

Related policies: M5.001.004 Pegfilgrastrim ( Retired )

Related Articles:

None

CSF Hematopoietic Colony Stimulating Factors

Population Reference No.

Populations

Interventions

Individuals

· With cancer receiving cytotoxic antineoplastic therapy sufficient to adversely affect myelopoiesis

Intervention of interest are:

· Hemaotopoietic Colony Stimulating Factors

Summary

White blood cell growth factors, also known as granulocyte colony stimulating factors (G-CSF), are administered to enhance recovery of blood related functions in neutropenia (low white blood count) including febrile neutropenia (FN). G-CSF is classified as a recombinant hematopoietic stimulant. This is not a cancer chemotherapy agent. It is a class II hematopoietic growth factor which acts on progenitor cells capable of forming a single differentiated cell type, the neutrophilic granulocyte, and is thus lineage-specific.

CSFs are also utilized to decrease the incidence and severity of infection associated with select disease-related and drug-related myelosuppression (inhibition of bone marrow function).

General Information

Prophylactic use of pegfilgrastim in patients undergoing chemotherapy reduces the risk of febrile neutropenia and infections. Prophylactic therapy can be considered for patients receiving myelosuppressive chemotherapy if the risk of febrile neutropenia is 20% or greater.

Pegfilgrastim-jmdb, pegfilgrastim-cbqv, pegfilgrastim-bmez and pegfilgrastim-apgf are leukocyte growth factors indicated to decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti- cancer drugs associated with a clinically significant incidence of febrile neutropenia.

Pegfilgrastim-jmdb, pegfilgrastim-cbqv, pegfilgrastim-bmez and pegfilgrastim-apgf are biosimilar* to pegfilgrastim.

*Biosimilar means that the biological product is approved based on data demonstrating that it is highly similar to an FDA-approved biological product, known as a reference product, and that there are no clinically meaningful differences between the biosimilar product and the reference product. Biosimilarity of pegfilgrastim-jmdb, pegfilgrastim-cbqv, pegfilgrastim-bmez and pegfilgrastim-apgf has been demonstrated for the condition(s) of use (e.g., indication(s), dosing regimen(s), strength(s), dosage form(s), and route(s) of administration described in its Full Prescribing Information).

Objective

The objective of this policy is to provide clinical criteria guidance.

COVERAGE INDICATIONS, LIMITATIONS, AND/OR MEDICAL NECESSITY

Filgrastim will be covered for Food and Drug Administration (FDA) approved labeled indications for cancer patients and severe chronic neutropenic patients when it is NOT self/caregiver administered. Please see the FDA drug label for the FDA approved indications and dosages. https://labels.fda.gov/

Additionally, Filgrastim will be considered medically reasonable and necessary for the following off-label indications when it is not self/caregiver administered:

AIDS leukopenia in children.
Amelioration of leukopenia in AIDS patients on AZT.
Amelioration of leukopenia in AIDS patients with chorioretinitis on Ganciclovir.
Intermittent administration of G-CSF for a subset of patients with myelodysplastic syndromes (MDS) who have severe neutropenia and recurrent infections.

Limitations

The following unlabeled uses of G-CSF have not been shown to be safe and effective and are noncovered: aplastic anemia, hairy cell leukemia, myeloid malignancies (other than AML), drug-induced and congenital agranulocytosis, and alloimmune neonatal neutropenia.
Therapeutic initiation of G-CSF does not add significantly to the antibiotic treatment outcome of established febrile neutropenia. Exceptions to this rule must be documented.
There are inadequate data to support the use of G-CSF for patients with afebrile neutropenia.
In general, for previously untreated patients receiving a chemotherapy regimen, primary administration of G-CSF is not considered medically necessary.
G-CSF should not be given within 24 hours before or after a dose of a chemotherapeutic agent, as rapidly dividing myeloid cells are potentially sensitive to these agents.
There is no evidence of benefit from the use of G-CSF to increase chemotherapy dose-intensity.
G-CSF should not be used concurrently with radiation therapy.

Notice: Services performed for any given diagnosis must meet all of the indications and limitations stated in this policy, the general requirements for medical necessity as stated in CMS payment policy manuals, any and all existing CMS national coverage determinations, and all Medicare payment rules.

Pegfilgrastim is a colony stimulating factor (CSF) that acts on hematopoietic cells by binding to specific cell surface receptors thereby, stimulating proliferation, differentiation, commitment, and end cell functional activation.

Pegfilgrastim is approved by the Food and Drug Administration to decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia.

Covered Indications
Pegfilgrastim will be covered for Food and Drug Administration (FDA) approved label indications. Please see the FDA drug label for the FDA approved indications and dosages. https://labels.fda.gov/.
Pegfilgrastim-jmdb, pegfilgrastim-cbqv, pegfilgrastim-bmez and pegfilgrastim-apgf will be covered for Food and Drug Administration (FDA) approved label indications. Please see the FDA drug label for the FDA approved indications and dosages. https://labels.fda.gov/.
The recommended dosage of pegfilgrastim is 6 mg administered once per chemotherapy cycle.
The administration should not occur within 14 days before, and 24 hours after, administration of cytotoxic chemotherapy. The following off-label exception to this rule will be allowed as follows:
If the patient is on a dose dense 14 day chemotherapy cycle, it would be acceptable to administer pegfilgrastim outside of the 14 day before and 24 hour after rule for chemotherapy. Pegfilgrastim would typically be administered on the second day of the 14-day dose dense chemotherapy cycle. An example of this would be a patient receiving dose dense cytoxan/adriamycin and taxol for breast cancer. The chemotherapy drug record/orders should indicate that the patient is on a 14-day dose dense chemotherapy schedule.
•
Limitations
Pegfilgrastim-jmdb, pegfilgrastim-cbqv, pegfilgrastim-bmez and pegfilgrastim-apgf are not indicated for the mobilization of peripheral blood progenitor cells for hematopoietic stem cell transplantation.
As published in the CMS IOM Publication 100-08, Medicare Program Integrity Manual, Chapter 13, Section 13.5.4, an item or service may be covered by a contractor LCD if it is reasonable and necessary under the Social Security Act Created on 11/23/2021. Page 3 of 8
Section 1862 (a)(1)(A). Contractors shall determine and describe the circumstances under which the item or service is considered reasonable and necessary.

The following table details the prescribing information for each agent:

CODE	BRAND NAME	FDA LABEL INDICATION	PACKAGE INSERT ADDRES	PREFERRED STATUS
J1442	Neupogen	NEUPOGEN is a leukocyte growth factor indicated to • Decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anticancer drugs associated with a significant incidence of severe neutropenia with fever (1.1) • Reduce the time to neutrophil recovery and the duration of fever, following induction or consolidation chemotherapy treatment of patients with acute myeloid leukemia (AML) (1.2) • Reduce the duration of neutropenia and neutropenia-related clinical sequelae‚ e.g.‚ febrile neutropenia, in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by bone marrow transplantation (BMT) (1.3) • Mobilize autologous hematopoietic progenitor cells into the peripheral blood for collection by leukapheresis (1.4) • Reduce the incidence and duration of sequelae of severe neutropenia (e.g.‚ fever‚ infections‚ oropharyngeal ulcers) in symptomatic patients with congenital neutropenia‚ cyclic neutropenia‚ or idiopathic neutropenia	https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/103353s5184lbl.pdf	Non Preferred
J1447	Granix	GRANIX (tbo-filgrastim) is a leukocyte growth factor indicated for reduction in the duration of severe neutropenia in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia.	https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/125294s035lbl.pdf	Non Preferred
J2506	NEULASTA	Neulasta is a leukocyte growth factor indicated to  Decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia. (1.1)  Increase survival in patients acutely exposed to myelosuppressive doses of radiation (Hematopoietic Subsyndrome of Acute Radiation Syndrome).	https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/125031s198lbl.pdf	Non Preferred
Q5101	ZARXIO	ZARXIO is a leukocyte growth factor indicated to: • Decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a significant incidence of severe neutropenia with fever (1.1) • Reduce the time to neutrophil recovery and the duration of fever, following induction or consolidation chemotherapy treatment of patients with acute myeloid leukemia (AML) (1.2) • Reduce the duration of neutropenia and neutropenia-related clinical sequelae‚ e.g.‚ febrile neutropenia, in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by bone marrow transplantation (BMT) (1.3) • Mobilize autologous hematopoietic progenitor cells into the peripheral blood for collection by leukapheresis (1.4) • Reduce the incidence and duration of sequelae of severe neutropenia (e.g.‚ fever‚ infections‚ oropharyngeal ulcers) in symptomatic patients with congenital neutropenia‚ cyclic neutropenia‚ or idiopathic neutropenia	https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/125553s007lbl.pdf	Preferred
Q5108	FULPHILA	Fulphila is a leukocyte growth factor indicated to • Decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia.	https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/761075s000lbl.pdf	Preferred
Q5110	NIVESTYM	NIVESTYM is a leukocyte growth factor indicated to • Decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a significant incidence of severe neutropenia with fever. (1.1) • Reduce the time to neutrophil recovery and the duration of fever, following induction or consolidation chemotherapy treatment of patients with acute myeloid leukemia (AML). (1.2) • Reduce the duration of neutropenia and neutropenia-related clinical sequelae‚ e.g.‚ febrile neutropenia, in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by bone marrow transplantation (BMT). (1.3) • Mobilize autologous hematopoietic progenitor cells into the peripheral blood for collection by leukapheresis. (1.4) • Reduce the incidence and duration of sequelae of severe neutropenia (e.g.‚ fever‚ infections‚ oropharyngeal ulcers) in symptomatic patients with congenital neutropenia‚ cyclic neutropenia‚ or idiopathic neutropenia	https://labeling.pfizer.com/ShowLabeling.aspx?id=10899	Non Preferred
Q5111	UDENYCA	UDENYCA is a leukocyte growth factor indicated to • Decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia. (1.1) • Increase survival in patients acutely exposed to myelosuppressive doses of radiation (Hematopoietic Subsyndrome of Acute Radiation Syndrome)	https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/761039s014lbl.pdf	Non Preferred
Q5120	ZIEXTENZO	ZIEXTENZO is a leukocyte growth factor indicated to decrease the incidence of infection, as manifested by febrile neutropenia, in patients with nonmyeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia. (	https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/761045lbl.pdf	Non Preferred
Q5122	NYVEPRIA	NYVEPRIA is a leukocyte growth factor indicated to decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia.	https://labeling.pfizer.com/ShowLabeling.aspx?id=13622	Non Preferred

Population

Reference No. 1

Policy Statement

[X] MedicallyNecessary

[ ] Investigational

Benefit Application

Triple-S Salud Preferred Drugs Determination

CSF-SA: First treatment of choice will be biosimilar Zarxio. In order to consider any other CSF-SA agents (Nivestym, Neupogen, Granix), patients must have documented previous use and therapeutic failure, intolerance or contraindication to biosimilar Zarxio.

CSF-LA: Fulphila is considered as preffered agent. In order to consider any other CSF-LA agents (Udenyca, Nyvepria, Neulasta or any other long-acting colony-stimulating factors) patients must have documented previous use and therapeutic failure, intolerance or contraindication to preffered agent.

Regulatory Status

IOM Citations

CMS IOM Publication 100-02, Medicare Benefit Policy Manual,
- Chapter 1, Section 30 Drugs and Biologicals
- Chapter 6, Section 20.5.3 Coverage of Outpatient Therapeutic Services Incident to a Physician’s Service Furnished on or After January 1, 2020 - Changes to Supervision Requirements
- Chapter 15, Section 50 Drugs and Biologicals, Section 60 Services and Supplies
CMS IOM Publication 100-04, Medicare Claims Processing Manual,
- Chapter 17 Drugs and Biologicals
- Chapter 23, Section 20.9 National Correct Coding Initiative (CCI)
CMS IOM Publication 100-08, Medicare Program Integrity Manual,
- Chapter 13, Section 13.5.4 Reasonable and Necessary Provision in an LCD

Social Security Act (Title XVIII) Standard References:

Title XVIII of the Social Security Act, Section 1861(t). This section addresses drugs and biologicals definitions.
Title XVIII of the Social Security Act, Section 1862(a)(1)(A) states that no Medicare payment shall be made for items or services which are not reasonable and necessary for the diagnosis or treatment of illness or injury.
Title XVIII of the Social Security Act, Section 1862(a)(7). This section excludes routine physical examinations.
Title XVIII of the Social Security Act, Section 1833(e) states that no payment shall be made to any provider for any claim that lacks the necessary information to process the claim.

Supplemental Information

Coding Guidance

Notice: It is not appropriate to bill Medicare for services that are not covered as if they are covered. When billing for non-covered services, use the appropriate modifier.

Utilization Guidelines

In accordance with CMS Ruling 95-1 (V), utilization of these services should be consistent with locally acceptable standards of practice.

Documentation Requirements

All documentation must be maintained in the patient's medical record and made available to the contractor upon request.
Every page of the record must be legible and include appropriate patient identification information (e.g., complete name, dates of service[s]). The documentation must include the legible signature of the physician or non-physician practitioner responsible for and providing the care to the patient.
The submitted medical record must support the use of the selected ICD-10-CM code(s). The submitted CPT/HCPCS code must describe the service performed.
Medical record documentation maintained by the physician must clearly indicate:
- The patient’s current absolute neutrophil count (ANC);
- The patient’s weight in kilograms;
- The administration and dosage of the G-CSF;
- The actual indication for which the drug was given and accompanying symptomology (e.g., fever); and
- The patient’s response to the treatment.

Dosage and Administration

For specific dosage and administration, please refer to the FDA approved drug label for recommended dosages for specific FDA indications. This can be accessed at https://labels.fda.gov/.

Medicare National Coverage

There was no LCD, NDC identified for PR region

This policy supplements but does not replace, modify or supersede existing Medicare applicable National Coverage Determinations (NCDs) or payment policy rules and regulations, federal statute or subsequent Medicare regulations regarding provision and payment for medical services.

Relevant CMS manual instructions and policies may be found in the following Internet-Only Manuals (IOMs) published on the CMS Web site.

References

First Coast Service Options, Inc. reference LCD number(s) – L28878, L29180, L29431, L28967, L29254, L29463
American Society of Clinical Oncology Growth Factor Expert Panel. (2000). Update recommendations for the use of hematopoietic colony-stimulating factors: Evidence-based, clinical practice guidelines.
Fauci, A.S., Braunwald, E., Isselbacher, K.J., et. al. (2004). Harrison’s principles of internal medicine (16th ed.). New York: McGraw-Hill.
Fischbach, F.T. (2003). A manual of laboratory and diagnostic tests (7th ed.). Philadelphia: J.B. Lippincott Company.
GRANIX® (tbo-filgrastim) injection.
National Comprehensive Cancer Network (NCCN) Drugs and Biologics Compendium® 2015 Filgrastim and Filgrastim-sndz. Retrieved on August 25, 2015. NIVESTYM™ (filgrastim-aafi) injection. Package Insert Neupogen® (Filgrastim). (2002). Amgen Inc.
Physician Desk Reference 2004.
The United States Pharmacopoeia Drug Information (USPDI). (2002). Oncology drug information. Maryland: The Association of Community Cancer Centers (ACCC).
Zarxio™ (filgrastim-sndz) injection, for subcutaneous or intravenous use FDA label. (2015)
CMS Article - Billing and Coding: Pegfilgrastim (A57725)
NYVEPRIA™ (pegfilgrastim-apgf) injection, for subcutaneous use Initial U.S. FDA Approval: 6/2020
The United States Pharmacopeia Drug Information (USP DI). (November 2005). Oncology drug information. The Association of Community Cancer Centers (ACCC). [On-Line].
UDENYCA™ (pegfilgrastim-cbqv) injection, for subcutaneous use Initial U.S. FDA Approval: 11/02/2018
ZIEXTENZO (pegfilgrastim-bmez) injection for subcutaneous use Initial U.S. Approval: 11/2019
Drug Facts and Comparisons NEWS. (January 2006). Pegfilgrastim, 2.
FULPHILA™ (pegfilgrastim-jmdb) injection, for subcutaneous use Initial U.S. Approval: 2018

Codes

Codes	Number	Description
HCPCS	J1442	Injection, filgrastim (G-CSF), excludes biosimilars, 1 mcg
	J1447	Injection, tbo-filgrastim, 1 mcg
	J2506	Injection, pegfilgrastim, 6 mg
	Q5101	Injection, filgrastim-sndz, (Zarxio), 1 mcg
	Q5110	Injection, filgrastim-aafi, biosimilar, (Nivestym), 1 mcg
	Q5108	Injection, pegfilgrastim-jmdb, biosimilar, (Fulphila), 0.5 mg
	Q5111	Injection, pegfilgrastim-cbqv, biosimilar, (Udenyca), 0.5 mg
	Q5120	Injection, pegfilgrastim-bmez, biosimilar, (ZIEXTENZO), 0.5 mg
	Q5122	Injection, pegfilgrastim-apgf, biosimilar, (Nyvepria), 0.5 mg
ICD-10-CM
Secondary Diagnosis Set	CODE	DESCRIPTION
	C00.0	Malignant neoplasm of external upper lip
	C00.1	Malignant neoplasm of external lower lip
	C00.2	Malignant neoplasm of external lip, unspecified
	C00.3	Malignant neoplasm of upper lip, inner aspect
	C00.4	Malignant neoplasm of lower lip, inner aspect
	C00.5	Malignant neoplasm of lip, unspecified, inner aspect
	C00.6	Malignant neoplasm of commissure of lip, unspecified
	C00.8	Malignant neoplasm of overlapping sites of lip
	C00.9	Malignant neoplasm of lip, unspecified
	C01	Malignant neoplasm of base of tongue
	C02.0	Malignant neoplasm of dorsal surface of tongue
	C02.1	Malignant neoplasm of border of tongue
	C02.2	Malignant neoplasm of ventral surface of tongue
	C02.3	Malignant neoplasm of anterior two-thirds of tongue, part unspecified
	C02.4	Malignant neoplasm of lingual tonsil
	C02.8	Malignant neoplasm of overlapping sites of tongue
	C02.9	Malignant neoplasm of tongue, unspecified
	C03.0	Malignant neoplasm of upper gum
	C03.1	Malignant neoplasm of lower gum
	C03.9	Malignant neoplasm of gum, unspecified
	C04.0	Malignant neoplasm of anterior floor of mouth
	C04.1	Malignant neoplasm of lateral floor of mouth
	C04.8	Malignant neoplasm of overlapping sites of floor of mouth
	C04.9	Malignant neoplasm of floor of mouth, unspecified
	C05.0	Malignant neoplasm of hard palate
	C05.1	Malignant neoplasm of soft palate
	C05.2	Malignant neoplasm of uvula
	C05.8	Malignant neoplasm of overlapping sites of palate
	C05.9	Malignant neoplasm of palate, unspecified
	C06.0	Malignant neoplasm of cheek mucosa
	C06.1	Malignant neoplasm of vestibule of mouth
	C06.2	Malignant neoplasm of retromolar area
	C06.80	Malignant neoplasm of overlapping sites of unspecified parts of mouth
	C06.89	Malignant neoplasm of overlapping sites of other parts of mouth
	C06.9	Malignant neoplasm of mouth, unspecified
	C07	Malignant neoplasm of parotid gland
	C08.0	Malignant neoplasm of submandibular gland
	C08.1	Malignant neoplasm of sublingual gland
	C08.9	Malignant neoplasm of major salivary gland, unspecified
	C09.0	Malignant neoplasm of tonsillar fossa
	C09.1	Malignant neoplasm of tonsillar pillar (anterior) (posterior)
	C09.8	Malignant neoplasm of overlapping sites of tonsil
	C09.9	Malignant neoplasm of tonsil, unspecified
	C10.0	Malignant neoplasm of vallecula
	C10.1	Malignant neoplasm of anterior surface of epiglottis
	C10.2	Malignant neoplasm of lateral wall of oropharynx
	C10.3	Malignant neoplasm of posterior wall of oropharynx
	C10.4	Malignant neoplasm of branchial cleft
	C10.8	Malignant neoplasm of overlapping sites of oropharynx
	C10.9	Malignant neoplasm of oropharynx, unspecified
	C11.0	Malignant neoplasm of superior wall of nasopharynx
	C11.1	Malignant neoplasm of posterior wall of nasopharynx
	C11.2	Malignant neoplasm of lateral wall of nasopharynx
	C11.3	Malignant neoplasm of anterior wall of nasopharynx
	C11.8	Malignant neoplasm of overlapping sites of nasopharynx
	C11.9	Malignant neoplasm of nasopharynx, unspecified
	C12	Malignant neoplasm of pyriform sinus
	C13.0	Malignant neoplasm of postcricoid region
	C13.1	Malignant neoplasm of aryepiglottic fold, hypopharyngeal aspect
	C13.2	Malignant neoplasm of posterior wall of hypopharynx
	C13.8	Malignant neoplasm of overlapping sites of hypopharynx
	C13.9	Malignant neoplasm of hypopharynx, unspecified
	C14.0	Malignant neoplasm of pharynx, unspecified
	C14.2	Malignant neoplasm of Waldeyer's ring
	C14.8	Malignant neoplasm of overlapping sites of lip, oral cavity and pharynx
	C15.3	Malignant neoplasm of upper third of esophagus
	C15.4	Malignant neoplasm of middle third of esophagus
	C15.5	Malignant neoplasm of lower third of esophagus
	C15.8	Malignant neoplasm of overlapping sites of esophagus
	C15.9	Malignant neoplasm of esophagus, unspecified
	C16.0	Malignant neoplasm of cardia
	C16.1	Malignant neoplasm of fundus of stomach
	C16.2	Malignant neoplasm of body of stomach
	C16.3	Malignant neoplasm of pyloric antrum
	C16.4	Malignant neoplasm of pylorus
	C16.5	Malignant neoplasm of lesser curvature of stomach, unspecified
	C16.6	Malignant neoplasm of greater curvature of stomach, unspecified
	C16.8	Malignant neoplasm of overlapping sites of stomach
	C16.9	Malignant neoplasm of stomach, unspecified
	C17.0	Malignant neoplasm of duodenum
	C17.1	Malignant neoplasm of jejunum
	C17.2	Malignant neoplasm of ileum
	C17.3	Meckel's diverticulum, malignant
	C17.8	Malignant neoplasm of overlapping sites of small intestine
	C17.9	Malignant neoplasm of small intestine, unspecified
	C18.0	Malignant neoplasm of cecum
	C18.1	Malignant neoplasm of appendix
	C18.2	Malignant neoplasm of ascending colon
	C18.3	Malignant neoplasm of hepatic flexure
	C18.4	Malignant neoplasm of transverse colon
	C18.5	Malignant neoplasm of splenic flexure
	C18.6	Malignant neoplasm of descending colon
	C18.7	Malignant neoplasm of sigmoid colon
	C18.8	Malignant neoplasm of overlapping sites of colon
	C18.9	Malignant neoplasm of colon, unspecified
	C19	Malignant neoplasm of rectosigmoid junction
	C20	Malignant neoplasm of rectum
	C21.0	Malignant neoplasm of anus, unspecified
	C21.1	Malignant neoplasm of anal canal
	C21.2	Malignant neoplasm of cloacogenic zone
	C21.8	Malignant neoplasm of overlapping sites of rectum, anus and anal canal
	C22.0	Liver cell carcinoma
	C22.1	Intrahepatic bile duct carcinoma
	C22.2	Hepatoblastoma
	C22.3	Angiosarcoma of liver
	C22.4	Other sarcomas of liver
	C22.7	Other specified carcinomas of liver
	C22.8	Malignant neoplasm of liver, primary, unspecified as to type
	C22.9	Malignant neoplasm of liver, not specified as primary or secondary
	C23	Malignant neoplasm of gallbladder
	C24.0	Malignant neoplasm of extrahepatic bile duct
	C24.1	Malignant neoplasm of ampulla of Vater
	C24.8	Malignant neoplasm of overlapping sites of biliary tract
	C24.9	Malignant neoplasm of biliary tract, unspecified
	C25.0	Malignant neoplasm of head of pancreas
	C25.1	Malignant neoplasm of body of pancreas
	C25.2	Malignant neoplasm of tail of pancreas
	C25.3	Malignant neoplasm of pancreatic duct
	C25.4	Malignant neoplasm of endocrine pancreas
	C25.7	Malignant neoplasm of other parts of pancreas
	C25.8	Malignant neoplasm of overlapping sites of pancreas
	C25.9	Malignant neoplasm of pancreas, unspecified
	C26.0	Malignant neoplasm of intestinal tract, part unspecified
	C26.1	Malignant neoplasm of spleen
	C26.9	Malignant neoplasm of ill-defined sites within the digestive system
	C30.0	Malignant neoplasm of nasal cavity
	C30.1	Malignant neoplasm of middle ear
	C31.0	Malignant neoplasm of maxillary sinus
	C31.1	Malignant neoplasm of ethmoidal sinus
	C31.2	Malignant neoplasm of frontal sinus
	C31.3	Malignant neoplasm of sphenoid sinus
	C31.8	Malignant neoplasm of overlapping sites of accessory sinuses
	C31.9	Malignant neoplasm of accessory sinus, unspecified
	C32.0	Malignant neoplasm of glottis
	C32.1	Malignant neoplasm of supraglottis
	C32.2	Malignant neoplasm of subglottis
	C32.3	Malignant neoplasm of laryngeal cartilage
	C32.8	Malignant neoplasm of overlapping sites of larynx
	C32.9	Malignant neoplasm of larynx, unspecified
	C33	Malignant neoplasm of trachea
	C34.00	Malignant neoplasm of unspecified main bronchus
	C34.01	Malignant neoplasm of right main bronchus
	C34.02	Malignant neoplasm of left main bronchus
	C34.10	Malignant neoplasm of upper lobe, unspecified bronchus or lung
	C34.11	Malignant neoplasm of upper lobe, right bronchus or lung
	C34.12	Malignant neoplasm of upper lobe, left bronchus or lung
	C34.2	Malignant neoplasm of middle lobe, bronchus or lung
	C34.30	Malignant neoplasm of lower lobe, unspecified bronchus or lung
	C34.31	Malignant neoplasm of lower lobe, right bronchus or lung
	C34.32	Malignant neoplasm of lower lobe, left bronchus or lung
	C34.80	Malignant neoplasm of overlapping sites of unspecified bronchus and lung
	C34.81	Malignant neoplasm of overlapping sites of right bronchus and lung
	C34.82	Malignant neoplasm of overlapping sites of left bronchus and lung
	C34.90	Malignant neoplasm of unspecified part of unspecified bronchus or lung
	C34.91	Malignant neoplasm of unspecified part of right bronchus or lung
	C34.92	Malignant neoplasm of unspecified part of left bronchus or lung
	C37	Malignant neoplasm of thymus
	C38.0	Malignant neoplasm of heart
	C38.1	Malignant neoplasm of anterior mediastinum
	C38.2	Malignant neoplasm of posterior mediastinum
	C38.3	Malignant neoplasm of mediastinum, part unspecified
	C38.4	Malignant neoplasm of pleura
	C38.8	Malignant neoplasm of overlapping sites of heart, mediastinum and pleura
	C39.0	Malignant neoplasm of upper respiratory tract, part unspecified
	C39.9	Malignant neoplasm of lower respiratory tract, part unspecified
	C40.00	Malignant neoplasm of scapula and long bones of unspecified upper limb
	C40.01	Malignant neoplasm of scapula and long bones of right upper limb
	C40.02	Malignant neoplasm of scapula and long bones of left upper limb
	C40.10	Malignant neoplasm of short bones of unspecified upper limb
	C40.11	Malignant neoplasm of short bones of right upper limb
	C40.12	Malignant neoplasm of short bones of left upper limb
	C40.20	Malignant neoplasm of long bones of unspecified lower limb
	C40.21	Malignant neoplasm of long bones of right lower limb
	C40.22	Malignant neoplasm of long bones of left lower limb
	C40.30	Malignant neoplasm of short bones of unspecified lower limb
	C40.31	Malignant neoplasm of short bones of right lower limb
	C40.32	Malignant neoplasm of short bones of left lower limb
	C40.80	Malignant neoplasm of overlapping sites of bone and articular cartilage of unspecified limb
	C40.81	Malignant neoplasm of overlapping sites of bone and articular cartilage of right limb
	C40.82	Malignant neoplasm of overlapping sites of bone and articular cartilage of left limb
	C40.90	Malignant neoplasm of unspecified bones and articular cartilage of unspecified limb
	C40.91	Malignant neoplasm of unspecified bones and articular cartilage of right limb
	C40.92	Malignant neoplasm of unspecified bones and articular cartilage of left limb
	C41.0	Malignant neoplasm of bones of skull and face
	C41.1	Malignant neoplasm of mandible
	C41.2	Malignant neoplasm of vertebral column
	C41.3	Malignant neoplasm of ribs, sternum and clavicle
	C41.4	Malignant neoplasm of pelvic bones, sacrum and coccyx
	C41.9	Malignant neoplasm of bone and articular cartilage, unspecified
	C43.0	Malignant melanoma of lip
	C43.10	Malignant melanoma of unspecified eyelid, including canthus
	C43.111	Malignant melanoma of right upper eyelid, including canthus
	C43.112	Malignant melanoma of right lower eyelid, including canthus
	C43.121	Malignant melanoma of left upper eyelid, including canthus
	C43.122	Malignant melanoma of left lower eyelid, including canthus
	C43.20	Malignant melanoma of unspecified ear and external auricular canal
	C43.21	Malignant melanoma of right ear and external auricular canal
	C43.22	Malignant melanoma of left ear and external auricular canal
	C43.30	Malignant melanoma of unspecified part of face
	C43.31	Malignant melanoma of nose
	C43.39	Malignant melanoma of other parts of face
	C43.4	Malignant melanoma of scalp and neck
	C43.51	Malignant melanoma of anal skin
	C43.52	Malignant melanoma of skin of breast
	C43.59	Malignant melanoma of other part of trunk
	C43.60	Malignant melanoma of unspecified upper limb, including shoulder
	C43.61	Malignant melanoma of right upper limb, including shoulder
	C43.62	Malignant melanoma of left upper limb, including shoulder
	C43.70	Malignant melanoma of unspecified lower limb, including hip
	C43.71	Malignant melanoma of right lower limb, including hip
	C43.72	Malignant melanoma of left lower limb, including hip
	C43.8	Malignant melanoma of overlapping sites of skin
	C43.9	Malignant melanoma of skin, unspecified
	C4A.0	Merkel cell carcinoma of lip
	C4A.10	Merkel cell carcinoma of unspecified eyelid, including canthus
	C4A.111	Merkel cell carcinoma of right upper eyelid, including canthus
	C4A.112	Merkel cell carcinoma of right lower eyelid, including canthus
	C4A.121	Merkel cell carcinoma of left upper eyelid, including canthus
	C4A.122	Merkel cell carcinoma of left lower eyelid, including canthus
	C4A.20	Merkel cell carcinoma of unspecified ear and external auricular canal
	C4A.21	Merkel cell carcinoma of right ear and external auricular canal
	C4A.22	Merkel cell carcinoma of left ear and external auricular canal
	C4A.30	Merkel cell carcinoma of unspecified part of face
	C4A.31	Merkel cell carcinoma of nose
	C4A.39	Merkel cell carcinoma of other parts of face
	C4A.4	Merkel cell carcinoma of scalp and neck
	C4A.51	Merkel cell carcinoma of anal skin
	C4A.52	Merkel cell carcinoma of skin of breast
	C4A.59	Merkel cell carcinoma of other part of trunk
	C4A.60	Merkel cell carcinoma of unspecified upper limb, including shoulder
	C4A.61	Merkel cell carcinoma of right upper limb, including shoulder
	C4A.62	Merkel cell carcinoma of left upper limb, including shoulder
	C4A.70	Merkel cell carcinoma of unspecified lower limb, including hip
	C4A.71	Merkel cell carcinoma of right lower limb, including hip
	C4A.72	Merkel cell carcinoma of left lower limb, including hip
	C4A.8	Merkel cell carcinoma of overlapping sites
	C4A.9	Merkel cell carcinoma, unspecified
	C44.00	Unspecified malignant neoplasm of skin of lip
	C44.01	Basal cell carcinoma of skin of lip
	C44.02	Squamous cell carcinoma of skin of lip
	C44.09	Other specified malignant neoplasm of skin of lip
	C44.101	Unspecified malignant neoplasm of skin of unspecified eyelid, including canthus
	C44.1021	Unspecified malignant neoplasm of skin of right upper eyelid, including canthus
	C44.1022	Unspecified malignant neoplasm of skin of right lower eyelid, including canthus
	C44.1091	Unspecified malignant neoplasm of skin of left upper eyelid, including canthus
	C44.1092	Unspecified malignant neoplasm of skin of left lower eyelid, including canthus
	C44.111	Basal cell carcinoma of skin of unspecified eyelid, including canthus
	C44.1121	Basal cell carcinoma of skin of right upper eyelid, including canthus
	C44.1122	Basal cell carcinoma of skin of right lower eyelid, including canthus
	C44.1191	Basal cell carcinoma of skin of left upper eyelid, including canthus
	C44.1192	Basal cell carcinoma of skin of left lower eyelid, including canthus
	C44.121	Squamous cell carcinoma of skin of unspecified eyelid, including canthus
	C44.1221	Squamous cell carcinoma of skin of right upper eyelid, including canthus
	C44.1222	Squamous cell carcinoma of skin of right lower eyelid, including canthus
	C44.1291	Squamous cell carcinoma of skin of left upper eyelid, including canthus
	C44.1292	Squamous cell carcinoma of skin of left lower eyelid, including canthus
	C44.131	Sebaceous cell carcinoma of skin of unspecified eyelid, including canthus
	C44.1321	Sebaceous cell carcinoma of skin of right upper eyelid, including canthus
	C44.1322	Sebaceous cell carcinoma of skin of right lower eyelid, including canthus
	C44.1391	Sebaceous cell carcinoma of skin of left upper eyelid, including canthus
	C44.1392	Sebaceous cell carcinoma of skin of left lower eyelid, including canthus
	C44.191	Other specified malignant neoplasm of skin of unspecified eyelid, including canthus
	C44.1921	Other specified malignant neoplasm of skin of right upper eyelid, including canthus
	C44.1922	Other specified malignant neoplasm of skin of right lower eyelid, including canthus
	C44.1991	Other specified malignant neoplasm of skin of left upper eyelid, including canthus
	C44.1992	Other specified malignant neoplasm of skin of left lower eyelid, including canthus
	C44.201	Unspecified malignant neoplasm of skin of unspecified ear and external auricular canal
	C44.202	Unspecified malignant neoplasm of skin of right ear and external auricular canal
	C44.209	Unspecified malignant neoplasm of skin of left ear and external auricular canal
	C44.211	Basal cell carcinoma of skin of unspecified ear and external auricular canal
	C44.212	Basal cell carcinoma of skin of right ear and external auricular canal
	C44.219	Basal cell carcinoma of skin of left ear and external auricular canal
	C44.221	Squamous cell carcinoma of skin of unspecified ear and external auricular canal
	C44.222	Squamous cell carcinoma of skin of right ear and external auricular canal
	C44.229	Squamous cell carcinoma of skin of left ear and external auricular canal
	C44.291	Other specified malignant neoplasm of skin of unspecified ear and external auricular canal
	C44.292	Other specified malignant neoplasm of skin of right ear and external auricular canal
	C44.299	Other specified malignant neoplasm of skin of left ear and external auricular canal
	C44.300	Unspecified malignant neoplasm of skin of unspecified part of face
	C44.301	Unspecified malignant neoplasm of skin of nose
	C44.309	Unspecified malignant neoplasm of skin of other parts of face
	C44.310	Basal cell carcinoma of skin of unspecified parts of face
	C44.311	Basal cell carcinoma of skin of nose
	C44.319	Basal cell carcinoma of skin of other parts of face
	C44.320	Squamous cell carcinoma of skin of unspecified parts of face
	C44.321	Squamous cell carcinoma of skin of nose
	C44.329	Squamous cell carcinoma of skin of other parts of face
	C44.390	Other specified malignant neoplasm of skin of unspecified parts of face
	C44.391	Other specified malignant neoplasm of skin of nose
	C44.399	Other specified malignant neoplasm of skin of other parts of face
	C44.40	Unspecified malignant neoplasm of skin of scalp and neck
	C44.41	Basal cell carcinoma of skin of scalp and neck
	C44.42	Squamous cell carcinoma of skin of scalp and neck
	C44.49	Other specified malignant neoplasm of skin of scalp and neck
	C44.500	Unspecified malignant neoplasm of anal skin
	C44.501	Unspecified malignant neoplasm of skin of breast
	C44.509	Unspecified malignant neoplasm of skin of other part of trunk
	C44.510	Basal cell carcinoma of anal skin
	C44.511	Basal cell carcinoma of skin of breast
	C44.519	Basal cell carcinoma of skin of other part of trunk
	C44.520	Squamous cell carcinoma of anal skin
	C44.521	Squamous cell carcinoma of skin of breast
	C44.529	Squamous cell carcinoma of skin of other part of trunk
	C44.590	Other specified malignant neoplasm of anal skin
	C44.591	Other specified malignant neoplasm of skin of breast
	C44.599	Other specified malignant neoplasm of skin of other part of trunk
	C44.601	Unspecified malignant neoplasm of skin of unspecified upper limb, including shoulder
	C44.602	Unspecified malignant neoplasm of skin of right upper limb, including shoulder
	C44.609	Unspecified malignant neoplasm of skin of left upper limb, including shoulder
	C44.611	Basal cell carcinoma of skin of unspecified upper limb, including shoulder
	C44.612	Basal cell carcinoma of skin of right upper limb, including shoulder
	C44.619	Basal cell carcinoma of skin of left upper limb, including shoulder
	C44.621	Squamous cell carcinoma of skin of unspecified upper limb, including shoulder
	C44.622	Squamous cell carcinoma of skin of right upper limb, including shoulder
	C44.629	Squamous cell carcinoma of skin of left upper limb, including shoulder
	C44.691	Other specified malignant neoplasm of skin of unspecified upper limb, including shoulder
	C44.692	Other specified malignant neoplasm of skin of right upper limb, including shoulder
	C44.699	Other specified malignant neoplasm of skin of left upper limb, including shoulder
	C44.701	Unspecified malignant neoplasm of skin of unspecified lower limb, including hip
	C44.702	Unspecified malignant neoplasm of skin of right lower limb, including hip
	C44.709	Unspecified malignant neoplasm of skin of left lower limb, including hip
	C44.711	Basal cell carcinoma of skin of unspecified lower limb, including hip
	C44.712	Basal cell carcinoma of skin of right lower limb, including hip
	C44.719	Basal cell carcinoma of skin of left lower limb, including hip
	C44.721	Squamous cell carcinoma of skin of unspecified lower limb, including hip
	C44.722	Squamous cell carcinoma of skin of right lower limb, including hip
	C44.729	Squamous cell carcinoma of skin of left lower limb, including hip
	C44.791	Other specified malignant neoplasm of skin of unspecified lower limb, including hip
	C44.792	Other specified malignant neoplasm of skin of right lower limb, including hip
	C44.799	Other specified malignant neoplasm of skin of left lower limb, including hip
	C44.80	Unspecified malignant neoplasm of overlapping sites of skin
	C44.81	Basal cell carcinoma of overlapping sites of skin
	C44.82	Squamous cell carcinoma of overlapping sites of skin
	C44.89	Other specified malignant neoplasm of overlapping sites of skin
	C44.90	Unspecified malignant neoplasm of skin, unspecified
	C44.91	Basal cell carcinoma of skin, unspecified
	C44.92	Squamous cell carcinoma of skin, unspecified
	C44.99	Other specified malignant neoplasm of skin, unspecified
	C45.0	Mesothelioma of pleura
	C45.1	Mesothelioma of peritoneum
	C45.2	Mesothelioma of pericardium
	C45.7	Mesothelioma of other sites
	C45.9	Mesothelioma, unspecified
	C46.0	Kaposi's sarcoma of skin
	C46.1	Kaposi's sarcoma of soft tissue
	C46.2	Kaposi's sarcoma of palate
	C46.3	Kaposi's sarcoma of lymph nodes
	C46.4	Kaposi's sarcoma of gastrointestinal sites
	C46.50	Kaposi's sarcoma of unspecified lung
	C46.51	Kaposi's sarcoma of right lung
	C46.52	Kaposi's sarcoma of left lung
	C46.7	Kaposi's sarcoma of other sites
	C46.9	Kaposi's sarcoma, unspecified
	C47.0	Malignant neoplasm of peripheral nerves of head, face and neck
	C47.10	Malignant neoplasm of peripheral nerves of unspecified upper limb, including shoulder
	C47.11	Malignant neoplasm of peripheral nerves of right upper limb, including shoulder
	C47.12	Malignant neoplasm of peripheral nerves of left upper limb, including shoulder
	C47.20	Malignant neoplasm of peripheral nerves of unspecified lower limb, including hip
	C47.21	Malignant neoplasm of peripheral nerves of right lower limb, including hip
	C47.22	Malignant neoplasm of peripheral nerves of left lower limb, including hip
	C47.3	Malignant neoplasm of peripheral nerves of thorax
	C47.4	Malignant neoplasm of peripheral nerves of abdomen
	C47.5	Malignant neoplasm of peripheral nerves of pelvis
	C47.6	Malignant neoplasm of peripheral nerves of trunk, unspecified
	C47.8	Malignant neoplasm of overlapping sites of peripheral nerves and autonomic nervous system
	C47.9	Malignant neoplasm of peripheral nerves and autonomic nervous system, unspecified
	C48.0	Malignant neoplasm of retroperitoneum
	C48.1	Malignant neoplasm of specified parts of peritoneum
	C48.2	Malignant neoplasm of peritoneum, unspecified
	C48.8	Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum
	C49.0	Malignant neoplasm of connective and soft tissue of head, face and neck
	C49.10	Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder
	C49.11	Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder
	C49.12	Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder
	C49.20	Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip
	C49.21	Malignant neoplasm of connective and soft tissue of right lower limb, including hip
	C49.22	Malignant neoplasm of connective and soft tissue of left lower limb, including hip
	C49.3	Malignant neoplasm of connective and soft tissue of thorax
	C49.4	Malignant neoplasm of connective and soft tissue of abdomen
	C49.5	Malignant neoplasm of connective and soft tissue of pelvis
	C49.6	Malignant neoplasm of connective and soft tissue of trunk, unspecified
	C49.8	Malignant neoplasm of overlapping sites of connective and soft tissue
	C49.9	Malignant neoplasm of connective and soft tissue, unspecified
	C49.A0	Gastrointestinal stromal tumor, unspecified site
	C49.A1	Gastrointestinal stromal tumor of esophagus
	C49.A2	Gastrointestinal stromal tumor of stomach
	C49.A3	Gastrointestinal stromal tumor of small intestine
	C49.A4	Gastrointestinal stromal tumor of large intestine
	C49.A5	Gastrointestinal stromal tumor of rectum
	C49.A9	Gastrointestinal stromal tumor of other sites
	C50.011	Malignant neoplasm of nipple and areola, right female breast
	C50.012	Malignant neoplasm of nipple and areola, left female breast
	C50.019	Malignant neoplasm of nipple and areola, unspecified female breast
	C50.021	Malignant neoplasm of nipple and areola, right male breast
	C50.022	Malignant neoplasm of nipple and areola, left male breast
	C50.029	Malignant neoplasm of nipple and areola, unspecified male breast
	C50.111	Malignant neoplasm of central portion of right female breast
	C50.112	Malignant neoplasm of central portion of left female breast
	C50.119	Malignant neoplasm of central portion of unspecified female breast
	C50.121	Malignant neoplasm of central portion of right male breast
	C50.122	Malignant neoplasm of central portion of left male breast
	C50.129	Malignant neoplasm of central portion of unspecified male breast
	C50.211	Malignant neoplasm of upper-inner quadrant of right female breast
	C50.212	Malignant neoplasm of upper-inner quadrant of left female breast
	C50.219	Malignant neoplasm of upper-inner quadrant of unspecified female breast
	C50.221	Malignant neoplasm of upper-inner quadrant of right male breast
	C50.222	Malignant neoplasm of upper-inner quadrant of left male breast
	C50.229	Malignant neoplasm of upper-inner quadrant of unspecified male breast
	C50.311	Malignant neoplasm of lower-inner quadrant of right female breast
	CODE	DESCRIPTION
	C50.312	Malignant neoplasm of lower-inner quadrant of left female breast
	C50.319	Malignant neoplasm of lower-inner quadrant of unspecified female breast
	C50.321	Malignant neoplasm of lower-inner quadrant of right male breast
	C50.322	Malignant neoplasm of lower-inner quadrant of left male breast
	C50.329	Malignant neoplasm of lower-inner quadrant of unspecified male breast
	C50.411	Malignant neoplasm of upper-outer quadrant of right female breast
	C50.412	Malignant neoplasm of upper-outer quadrant of left female breast
	C50.419	Malignant neoplasm of upper-outer quadrant of unspecified female breast
	C50.421	Malignant neoplasm of upper-outer quadrant of right male breast
	C50.422	Malignant neoplasm of upper-outer quadrant of left male breast
	C50.429	Malignant neoplasm of upper-outer quadrant of unspecified male breast
	C50.511	Malignant neoplasm of lower-outer quadrant of right female breast
	C50.512	Malignant neoplasm of lower-outer quadrant of left female breast
	C50.519	Malignant neoplasm of lower-outer quadrant of unspecified female breast
	C50.521	Malignant neoplasm of lower-outer quadrant of right male breast
	C50.522	Malignant neoplasm of lower-outer quadrant of left male breast
	C50.529	Malignant neoplasm of lower-outer quadrant of unspecified male breast
	C50.611	Malignant neoplasm of axillary tail of right female breast
	C50.612	Malignant neoplasm of axillary tail of left female breast
	C50.619	Malignant neoplasm of axillary tail of unspecified female breast
	C50.621	Malignant neoplasm of axillary tail of right male breast
	C50.622	Malignant neoplasm of axillary tail of left male breast
	C50.629	Malignant neoplasm of axillary tail of unspecified male breast
	C50.811	Malignant neoplasm of overlapping sites of right female breast
	C50.812	Malignant neoplasm of overlapping sites of left female breast
	C50.819	Malignant neoplasm of overlapping sites of unspecified female breast
	C50.821	Malignant neoplasm of overlapping sites of right male breast
	C50.822	Malignant neoplasm of overlapping sites of left male breast
	C50.829	Malignant neoplasm of overlapping sites of unspecified male breast
	C50.911	Malignant neoplasm of unspecified site of right female breast
	C50.912	Malignant neoplasm of unspecified site of left female breast
	C50.919	Malignant neoplasm of unspecified site of unspecified female breast
	C50.921	Malignant neoplasm of unspecified site of right male breast
	C50.922	Malignant neoplasm of unspecified site of left male breast
	C50.929	Malignant neoplasm of unspecified site of unspecified male breast
	C51.0	Malignant neoplasm of labium majus
	C51.1	Malignant neoplasm of labium minus
	C51.2	Malignant neoplasm of clitoris
	C51.8	Malignant neoplasm of overlapping sites of vulva
	C51.9	Malignant neoplasm of vulva, unspecified
	C52	Malignant neoplasm of vagina
	C53.0	Malignant neoplasm of endocervix
	C53.1	Malignant neoplasm of exocervix
	C53.8	Malignant neoplasm of overlapping sites of cervix uteri
	C53.9	Malignant neoplasm of cervix uteri, unspecified
	C54.0	Malignant neoplasm of isthmus uteri
	C54.1	Malignant neoplasm of endometrium
	C54.2	Malignant neoplasm of myometrium
	C54.3	Malignant neoplasm of fundus uteri
	C54.8	Malignant neoplasm of overlapping sites of corpus uteri
	C54.9	Malignant neoplasm of corpus uteri, unspecified
	C55	Malignant neoplasm of uterus, part unspecified
	C56.1	Malignant neoplasm of right ovary
	C56.2	Malignant neoplasm of left ovary
	C56.9	Malignant neoplasm of unspecified ovary
	C57.00	Malignant neoplasm of unspecified fallopian tube
	C57.01	Malignant neoplasm of right fallopian tube
	C57.02	Malignant neoplasm of left fallopian tube
	C57.10	Malignant neoplasm of unspecified broad ligament
	C57.11	Malignant neoplasm of right broad ligament
	C57.12	Malignant neoplasm of left broad ligament
	C57.20	Malignant neoplasm of unspecified round ligament
	C57.21	Malignant neoplasm of right round ligament
	C57.22	Malignant neoplasm of left round ligament
	C57.3	Malignant neoplasm of parametrium
	C57.4	Malignant neoplasm of uterine adnexa, unspecified
	C57.7	Malignant neoplasm of other specified female genital organs
	C57.8	Malignant neoplasm of overlapping sites of female genital organs
	C57.9	Malignant neoplasm of female genital organ, unspecified
	C58	Malignant neoplasm of placenta
	C60.0	Malignant neoplasm of prepuce
	C60.1	Malignant neoplasm of glans penis
	C60.2	Malignant neoplasm of body of penis
	C60.8	Malignant neoplasm of overlapping sites of penis
	C60.9	Malignant neoplasm of penis, unspecified
	C61	Malignant neoplasm of prostate
	C62.00	Malignant neoplasm of unspecified undescended testis
	C62.01	Malignant neoplasm of undescended right testis
	C62.02	Malignant neoplasm of undescended left testis
	C62.10	Malignant neoplasm of unspecified descended testis
	C62.11	Malignant neoplasm of descended right testis
	C62.12	Malignant neoplasm of descended left testis
	C62.90	Malignant neoplasm of unspecified testis, unspecified whether descended or undescended
	C62.91	Malignant neoplasm of right testis, unspecified whether descended or undescended
	C62.92	Malignant neoplasm of left testis, unspecified whether descended or undescended
	C63.00	Malignant neoplasm of unspecified epididymis
	C63.01	Malignant neoplasm of right epididymis
	C63.02	Malignant neoplasm of left epididymis
	C63.10	Malignant neoplasm of unspecified spermatic cord
	C63.11	Malignant neoplasm of right spermatic cord
	C63.12	Malignant neoplasm of left spermatic cord
	C63.2	Malignant neoplasm of scrotum
	C63.7	Malignant neoplasm of other specified male genital organs
	C63.8	Malignant neoplasm of overlapping sites of male genital organs
	C63.9	Malignant neoplasm of male genital organ, unspecified
	C64.1	Malignant neoplasm of right kidney, except renal pelvis
	C64.2	Malignant neoplasm of left kidney, except renal pelvis
	C64.9	Malignant neoplasm of unspecified kidney, except renal pelvis
	C65.1	Malignant neoplasm of right renal pelvis
	C65.2	Malignant neoplasm of left renal pelvis
	C65.9	Malignant neoplasm of unspecified renal pelvis
	C66.1	Malignant neoplasm of right ureter
	C66.2	Malignant neoplasm of left ureter
	C66.9	Malignant neoplasm of unspecified ureter
	C67.0	Malignant neoplasm of trigone of bladder
	C67.1	Malignant neoplasm of dome of bladder
	C67.2	Malignant neoplasm of lateral wall of bladder
	C67.3	Malignant neoplasm of anterior wall of bladder
	C67.4	Malignant neoplasm of posterior wall of bladder
	C67.5	Malignant neoplasm of bladder neck
	C67.6	Malignant neoplasm of ureteric orifice
	C67.7	Malignant neoplasm of urachus
	C67.8	Malignant neoplasm of overlapping sites of bladder
	C67.9	Malignant neoplasm of bladder, unspecified
	C68.0	Malignant neoplasm of urethra
	C68.1	Malignant neoplasm of paraurethral glands
	C68.8	Malignant neoplasm of overlapping sites of urinary organs
	C68.9	Malignant neoplasm of urinary organ, unspecified
	C69.00	Malignant neoplasm of unspecified conjunctiva
	C69.01	Malignant neoplasm of right conjunctiva
	C69.02	Malignant neoplasm of left conjunctiva
	C69.10	Malignant neoplasm of unspecified cornea
	C69.11	Malignant neoplasm of right cornea
	C69.12	Malignant neoplasm of left cornea
	C69.20	Malignant neoplasm of unspecified retina
	C69.21	Malignant neoplasm of right retina
	C69.22	Malignant neoplasm of left retina
	C69.30	Malignant neoplasm of unspecified choroid
	C69.31	Malignant neoplasm of right choroid
	C69.32	Malignant neoplasm of left choroid
	C69.40	Malignant neoplasm of unspecified ciliary body
	C69.41	Malignant neoplasm of right ciliary body
	C69.42	Malignant neoplasm of left ciliary body
	C69.50	Malignant neoplasm of unspecified lacrimal gland and duct
	C69.51	Malignant neoplasm of right lacrimal gland and duct
	C69.52	Malignant neoplasm of left lacrimal gland and duct
	C69.60	Malignant neoplasm of unspecified orbit
	C69.61	Malignant neoplasm of right orbit
	C69.62	Malignant neoplasm of left orbit
	C69.80	Malignant neoplasm of overlapping sites of unspecified eye and adnexa
	C69.81	Malignant neoplasm of overlapping sites of right eye and adnexa
	C69.82	Malignant neoplasm of overlapping sites of left eye and adnexa
	C69.90	Malignant neoplasm of unspecified site of unspecified eye
	C69.91	Malignant neoplasm of unspecified site of right eye
	C69.92	Malignant neoplasm of unspecified site of left eye
	C70.0	Malignant neoplasm of cerebral meninges
	C70.1	Malignant neoplasm of spinal meninges
	C70.9	Malignant neoplasm of meninges, unspecified
	C71.0	Malignant neoplasm of cerebrum, except lobes and ventricles
	C71.1	Malignant neoplasm of frontal lobe
	C71.2	Malignant neoplasm of temporal lobe
	C71.3	Malignant neoplasm of parietal lobe
	C71.4	Malignant neoplasm of occipital lobe
	C71.5	Malignant neoplasm of cerebral ventricle
	C71.6	Malignant neoplasm of cerebellum
	C71.7	Malignant neoplasm of brain stem
	C71.8	Malignant neoplasm of overlapping sites of brain
	C71.9	Malignant neoplasm of brain, unspecified
	C72.0	Malignant neoplasm of spinal cord
	C72.1	Malignant neoplasm of cauda equina
	C72.20	Malignant neoplasm of unspecified olfactory nerve
	C72.21	Malignant neoplasm of right olfactory nerve
	C72.22	Malignant neoplasm of left olfactory nerve
	C72.30	Malignant neoplasm of unspecified optic nerve
	C72.31	Malignant neoplasm of right optic nerve
	C72.32	Malignant neoplasm of left optic nerve
	C72.40	Malignant neoplasm of unspecified acoustic nerve
	C72.41	Malignant neoplasm of right acoustic nerve
	C72.42	Malignant neoplasm of left acoustic nerve
	C72.50	Malignant neoplasm of unspecified cranial nerve
	C72.59	Malignant neoplasm of other cranial nerves
	C72.9	Malignant neoplasm of central nervous system, unspecified
	C73	Malignant neoplasm of thyroid gland
	C74.00	Malignant neoplasm of cortex of unspecified adrenal gland
	C74.01	Malignant neoplasm of cortex of right adrenal gland
	C74.02	Malignant neoplasm of cortex of left adrenal gland
	C74.10	Malignant neoplasm of medulla of unspecified adrenal gland
	C74.11	Malignant neoplasm of medulla of right adrenal gland
	C74.12	Malignant neoplasm of medulla of left adrenal gland
	C74.90	Malignant neoplasm of unspecified part of unspecified adrenal gland
	C74.91	Malignant neoplasm of unspecified part of right adrenal gland
	C74.92	Malignant neoplasm of unspecified part of left adrenal gland
	C75.0	Malignant neoplasm of parathyroid gland
	C75.1	Malignant neoplasm of pituitary gland
	C75.2	Malignant neoplasm of craniopharyngeal duct
	C75.3	Malignant neoplasm of pineal gland
	C75.4	Malignant neoplasm of carotid body
	C75.5	Malignant neoplasm of aortic body and other paraganglia
	C75.8	Malignant neoplasm with pluriglandular involvement, unspecified
	C75.9	Malignant neoplasm of endocrine gland, unspecified
	C7A.1	Malignant poorly differentiated neuroendocrine tumors
	C7A.8	Other malignant neuroendocrine tumors
	C76.0	Malignant neoplasm of head, face and neck
	C76.1	Malignant neoplasm of thorax
	C76.2	Malignant neoplasm of abdomen
	C76.3	Malignant neoplasm of pelvis
	C76.40	Malignant neoplasm of unspecified upper limb
	C76.41	Malignant neoplasm of right upper limb
	C76.42	Malignant neoplasm of left upper limb
	C76.50	Malignant neoplasm of unspecified lower limb
	C76.51	Malignant neoplasm of right lower limb
	C76.52	Malignant neoplasm of left lower limb
	C76.8	Malignant neoplasm of other specified ill-defined sites
	C77.0	Secondary and unspecified malignant neoplasm of lymph nodes of head, face and neck
	C77.1	Secondary and unspecified malignant neoplasm of intrathoracic lymph nodes
	C77.2	Secondary and unspecified malignant neoplasm of intra-abdominal lymph nodes
	C77.3	Secondary and unspecified malignant neoplasm of axilla and upper limb lymph nodes
	C77.4	Secondary and unspecified malignant neoplasm of inguinal and lower limb lymph nodes
	C77.5	Secondary and unspecified malignant neoplasm of intrapelvic lymph nodes
	C77.8	Secondary and unspecified malignant neoplasm of lymph nodes of multiple regions
	C77.9	Secondary and unspecified malignant neoplasm of lymph node, unspecified
	C78.00	Secondary malignant neoplasm of unspecified lung
	C78.01	Secondary malignant neoplasm of right lung
	C78.02	Secondary malignant neoplasm of left lung
	C78.1	Secondary malignant neoplasm of mediastinum
	C78.2	Secondary malignant neoplasm of pleura
	C78.30	Secondary malignant neoplasm of unspecified respiratory organ
	C78.39	Secondary malignant neoplasm of other respiratory organs
	C78.4	Secondary malignant neoplasm of small intestine
	C78.5	Secondary malignant neoplasm of large intestine and rectum
	C78.6	Secondary malignant neoplasm of retroperitoneum and peritoneum
	C78.7	Secondary malignant neoplasm of liver and intrahepatic bile duct
	C78.80	Secondary malignant neoplasm of unspecified digestive organ
	C78.89	Secondary malignant neoplasm of other digestive organs
	C79.00	Secondary malignant neoplasm of unspecified kidney and renal pelvis
	C79.01	Secondary malignant neoplasm of right kidney and renal pelvis
	C79.02	Secondary malignant neoplasm of left kidney and renal pelvis
	C79.10	Secondary malignant neoplasm of unspecified urinary organs
	C79.11	Secondary malignant neoplasm of bladder
	C79.19	Secondary malignant neoplasm of other urinary organs
	C79.2	Secondary malignant neoplasm of skin
	C79.31	Secondary malignant neoplasm of brain
	C79.32	Secondary malignant neoplasm of cerebral meninges
	C79.40	Secondary malignant neoplasm of unspecified part of nervous system
	C79.49	Secondary malignant neoplasm of other parts of nervous system
	C79.51	Secondary malignant neoplasm of bone
	C79.52	Secondary malignant neoplasm of bone marrow
	C79.60	Secondary malignant neoplasm of unspecified ovary
	C79.61	Secondary malignant neoplasm of right ovary
	C79.62	Secondary malignant neoplasm of left ovary
	C79.70	Secondary malignant neoplasm of unspecified adrenal gland
	C79.71	Secondary malignant neoplasm of right adrenal gland
	C79.72	Secondary malignant neoplasm of left adrenal gland
	C79.81	Secondary malignant neoplasm of breast
	C79.82	Secondary malignant neoplasm of genital organs
	C79.89	Secondary malignant neoplasm of other specified sites
	C79.9	Secondary malignant neoplasm of unspecified site
	C80.0	Disseminated malignant neoplasm, unspecified
	C80.1	Malignant (primary) neoplasm, unspecified
	C80.2	Malignant neoplasm associated with transplanted organ
	C81.00	Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site
	C81.01	Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck
	C81.02	Nodular lymphocyte predominant Hodgkin lymphoma, intrathoracic lymph nodes
	C81.03	Nodular lymphocyte predominant Hodgkin lymphoma, intra-abdominal lymph nodes
	C81.04	Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of axilla and upper limb
	C81.05	Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
	C81.06	Nodular lymphocyte predominant Hodgkin lymphoma, intrapelvic lymph nodes
	C81.07	Nodular lymphocyte predominant Hodgkin lymphoma, spleen
	C81.08	Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of multiple sites
	C81.09	Nodular lymphocyte predominant Hodgkin lymphoma, extranodal and solid organ sites
	C81.10	Nodular sclerosis Hodgkin lymphoma, unspecified site
	C81.11	Nodular sclerosis Hodgkin lymphoma, lymph nodes of head, face, and neck
	C81.12	Nodular sclerosis Hodgkin lymphoma, intrathoracic lymph nodes
	C81.13	Nodular sclerosis Hodgkin lymphoma, intra-abdominal lymph nodes
	C81.14	Nodular sclerosis Hodgkin lymphoma, lymph nodes of axilla and upper limb
	C81.15	Nodular sclerosis Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
	C81.16	Nodular sclerosis Hodgkin lymphoma, intrapelvic lymph nodes
	C81.17	Nodular sclerosis Hodgkin lymphoma, spleen
	C81.18	Nodular sclerosis Hodgkin lymphoma, lymph nodes of multiple sites
	C81.19	Nodular sclerosis Hodgkin lymphoma, extranodal and solid organ sites
	C81.20	Mixed cellularity Hodgkin lymphoma, unspecified site
	C81.21	Mixed cellularity Hodgkin lymphoma, lymph nodes of head, face, and neck
	C81.22	Mixed cellularity Hodgkin lymphoma, intrathoracic lymph nodes
	C81.23	Mixed cellularity Hodgkin lymphoma, intra-abdominal lymph nodes
	C81.24	Mixed cellularity Hodgkin lymphoma, lymph nodes of axilla and upper limb
	C81.25	Mixed cellularity Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
	C81.26	Mixed cellularity Hodgkin lymphoma, intrapelvic lymph nodes
	C81.27	Mixed cellularity Hodgkin lymphoma, spleen
	C81.28	Mixed cellularity Hodgkin lymphoma, lymph nodes of multiple sites
	C81.29	Mixed cellularity Hodgkin lymphoma, extranodal and solid organ sites
	C81.30	Lymphocyte depleted Hodgkin lymphoma, unspecified site
	C81.31	Lymphocyte depleted Hodgkin lymphoma, lymph nodes of head, face, and neck
	C81.32	Lymphocyte depleted Hodgkin lymphoma, intrathoracic lymph nodes
	C81.33	Lymphocyte depleted Hodgkin lymphoma, intra-abdominal lymph nodes
	C81.34	Lymphocyte depleted Hodgkin lymphoma, lymph nodes of axilla and upper limb
	C81.35	Lymphocyte depleted Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
	C81.36	Lymphocyte depleted Hodgkin lymphoma, intrapelvic lymph nodes
	C81.37	Lymphocyte depleted Hodgkin lymphoma, spleen
	C81.38	Lymphocyte depleted Hodgkin lymphoma, lymph nodes of multiple sites
	C81.39	Lymphocyte depleted Hodgkin lymphoma, extranodal and solid organ sites
	C81.40	Lymphocyte-rich Hodgkin lymphoma, unspecified site
	C81.41	Lymphocyte-rich Hodgkin lymphoma, lymph nodes of head, face, and neck
	C81.42	Lymphocyte-rich Hodgkin lymphoma, intrathoracic lymph nodes
	C81.43	Lymphocyte-rich Hodgkin lymphoma, intra-abdominal lymph nodes
	C81.44	Lymphocyte-rich Hodgkin lymphoma, lymph nodes of axilla and upper limb
	C81.45	Lymphocyte-rich Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
	C81.46	Lymphocyte-rich Hodgkin lymphoma, intrapelvic lymph nodes
	C81.47	Lymphocyte-rich Hodgkin lymphoma, spleen
	C81.48	Lymphocyte-rich Hodgkin lymphoma, lymph nodes of multiple sites
	C81.49	Lymphocyte-rich Hodgkin lymphoma, extranodal and solid organ sites
	C81.70	Other Hodgkin lymphoma, unspecified site
	C81.71	Other Hodgkin lymphoma, lymph nodes of head, face, and neck
	C81.72	Other Hodgkin lymphoma, intrathoracic lymph nodes
	C81.73	Other Hodgkin lymphoma, intra-abdominal lymph nodes
	C81.74	Other Hodgkin lymphoma, lymph nodes of axilla and upper limb
	C81.75	Other Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
	C81.76	Other Hodgkin lymphoma, intrapelvic lymph nodes
	C81.77	Other Hodgkin lymphoma, spleen
	C81.78	Other Hodgkin lymphoma, lymph nodes of multiple sites
	C81.79	Other Hodgkin lymphoma, extranodal and solid organ sites
	C81.90	Hodgkin lymphoma, unspecified, unspecified site
	C81.91	Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck
	C81.92	Hodgkin lymphoma, unspecified, intrathoracic lymph nodes
	C81.93	Hodgkin lymphoma, unspecified, intra-abdominal lymph nodes
	C81.94	Hodgkin lymphoma, unspecified, lymph nodes of axilla and upper limb
	C81.95	Hodgkin lymphoma, unspecified, lymph nodes of inguinal region and lower limb
	C81.96	Hodgkin lymphoma, unspecified, intrapelvic lymph nodes
	C81.97	Hodgkin lymphoma, unspecified, spleen
	C81.98	Hodgkin lymphoma, unspecified, lymph nodes of multiple sites
	C81.99	Hodgkin lymphoma, unspecified, extranodal and solid organ sites
	C82.00	Follicular lymphoma grade I, unspecified site
	C82.01	Follicular lymphoma grade I, lymph nodes of head, face, and neck
	C82.02	Follicular lymphoma grade I, intrathoracic lymph nodes
	C82.03	Follicular lymphoma grade I, intra-abdominal lymph nodes
	C82.04	Follicular lymphoma grade I, lymph nodes of axilla and upper limb
	C82.05	Follicular lymphoma grade I, lymph nodes of inguinal region and lower limb
	C82.06	Follicular lymphoma grade I, intrapelvic lymph nodes
	C82.07	Follicular lymphoma grade I, spleen
	C82.08	Follicular lymphoma grade I, lymph nodes of multiple sites
	C82.09	Follicular lymphoma grade I, extranodal and solid organ sites
	C82.10	Follicular lymphoma grade II, unspecified site
	C82.11	Follicular lymphoma grade II, lymph nodes of head, face, and neck
	C82.12	Follicular lymphoma grade II, intrathoracic lymph nodes
	C82.13	Follicular lymphoma grade II, intra-abdominal lymph nodes
	C82.14	Follicular lymphoma grade II, lymph nodes of axilla and upper limb
	C82.15	Follicular lymphoma grade II, lymph nodes of inguinal region and lower limb
	C82.16	Follicular lymphoma grade II, intrapelvic lymph nodes
	C82.17	Follicular lymphoma grade II, spleen
	C82.18	Follicular lymphoma grade II, lymph nodes of multiple sites
	C82.19	Follicular lymphoma grade II, extranodal and solid organ sites
	C82.20	Follicular lymphoma grade III, unspecified, unspecified site
	C82.21	Follicular lymphoma grade III, unspecified, lymph nodes of head, face, and neck
	C82.22	Follicular lymphoma grade III, unspecified, intrathoracic lymph nodes
	C82.23	Follicular lymphoma grade III, unspecified, intra-abdominal lymph nodes
	C82.24	Follicular lymphoma grade III, unspecified, lymph nodes of axilla and upper limb
	C82.25	Follicular lymphoma grade III, unspecified, lymph nodes of inguinal region and lower limb
	C82.26	Follicular lymphoma grade III, unspecified, intrapelvic lymph nodes
	C82.27	Follicular lymphoma grade III, unspecified, spleen
	C82.28	Follicular lymphoma grade III, unspecified, lymph nodes of multiple sites
	C82.29	Follicular lymphoma grade III, unspecified, extranodal and solid organ sites
	C82.30	Follicular lymphoma grade IIIa, unspecified site
	C82.31	Follicular lymphoma grade IIIa, lymph nodes of head, face, and neck
	C82.32	Follicular lymphoma grade IIIa, intrathoracic lymph nodes
	C82.33	Follicular lymphoma grade IIIa, intra-abdominal lymph nodes
	C82.34	Follicular lymphoma grade IIIa, lymph nodes of axilla and upper limb
	C82.35	Follicular lymphoma grade IIIa, lymph nodes of inguinal region and lower limb
	C82.36	Follicular lymphoma grade IIIa, intrapelvic lymph nodes
	C82.37	Follicular lymphoma grade IIIa, spleen
	C82.38	Follicular lymphoma grade IIIa, lymph nodes of multiple sites
	C82.39	Follicular lymphoma grade IIIa, extranodal and solid organ sites
	C82.40	Follicular lymphoma grade IIIb, unspecified site
	C82.41	Follicular lymphoma grade IIIb, lymph nodes of head, face, and neck
	C82.42	Follicular lymphoma grade IIIb, intrathoracic lymph nodes
	C82.43	Follicular lymphoma grade IIIb, intra-abdominal lymph nodes
	C82.44	Follicular lymphoma grade IIIb, lymph nodes of axilla and upper limb
	C82.45	Follicular lymphoma grade IIIb, lymph nodes of inguinal region and lower limb
	C82.46	Follicular lymphoma grade IIIb, intrapelvic lymph nodes
	C82.47	Follicular lymphoma grade IIIb, spleen
	C82.48	Follicular lymphoma grade IIIb, lymph nodes of multiple sites
	C82.49	Follicular lymphoma grade IIIb, extranodal and solid organ sites
	C82.50	Diffuse follicle center lymphoma, unspecified site
	C82.51	Diffuse follicle center lymphoma, lymph nodes of head, face, and neck
	C82.52	Diffuse follicle center lymphoma, intrathoracic lymph nodes
	C82.53	Diffuse follicle center lymphoma, intra-abdominal lymph nodes
	C82.54	Diffuse follicle center lymphoma, lymph nodes of axilla and upper limb
	C82.55	Diffuse follicle center lymphoma, lymph nodes of inguinal region and lower limb
	C82.56	Diffuse follicle center lymphoma, intrapelvic lymph nodes
	C82.57	Diffuse follicle center lymphoma, spleen
	C82.58	Diffuse follicle center lymphoma, lymph nodes of multiple sites
	C82.59	Diffuse follicle center lymphoma, extranodal and solid organ sites
	C82.60	Cutaneous follicle center lymphoma, unspecified site
	C82.61	Cutaneous follicle center lymphoma, lymph nodes of head, face, and neck
	C82.62	Cutaneous follicle center lymphoma, intrathoracic lymph nodes
	C82.63	Cutaneous follicle center lymphoma, intra-abdominal lymph nodes
	C82.64	Cutaneous follicle center lymphoma, lymph nodes of axilla and upper limb
	C82.65	Cutaneous follicle center lymphoma, lymph nodes of inguinal region and lower limb
	C82.66	Cutaneous follicle center lymphoma, intrapelvic lymph nodes
	C82.67	Cutaneous follicle center lymphoma, spleen
	C82.68	Cutaneous follicle center lymphoma, lymph nodes of multiple sites
	C82.69	Cutaneous follicle center lymphoma, extranodal and solid organ sites
	C82.80	Other types of follicular lymphoma, unspecified site
	C82.81	Other types of follicular lymphoma, lymph nodes of head, face, and neck
	C82.82	Other types of follicular lymphoma, intrathoracic lymph nodes
	C82.83	Other types of follicular lymphoma, intra-abdominal lymph nodes
	C82.84	Other types of follicular lymphoma, lymph nodes of axilla and upper limb
	C82.85	Other types of follicular lymphoma, lymph nodes of inguinal region and lower limb
	C82.86	Other types of follicular lymphoma, intrapelvic lymph nodes
	C82.87	Other types of follicular lymphoma, spleen
	C82.88	Other types of follicular lymphoma, lymph nodes of multiple sites
	C82.89	Other types of follicular lymphoma, extranodal and solid organ sites
	C82.90	Follicular lymphoma, unspecified, unspecified site
	C82.91	Follicular lymphoma, unspecified, lymph nodes of head, face, and neck
	C82.92	Follicular lymphoma, unspecified, intrathoracic lymph nodes
	C82.93	Follicular lymphoma, unspecified, intra-abdominal lymph nodes
	C82.94	Follicular lymphoma, unspecified, lymph nodes of axilla and upper limb
	C82.95	Follicular lymphoma, unspecified, lymph nodes of inguinal region and lower limb
	C82.96	Follicular lymphoma, unspecified, intrapelvic lymph nodes
	C82.97	Follicular lymphoma, unspecified, spleen
	C82.98	Follicular lymphoma, unspecified, lymph nodes of multiple sites
	C82.99	Follicular lymphoma, unspecified, extranodal and solid organ sites
	C83.00	Small cell B-cell lymphoma, unspecified site
	C83.01	Small cell B-cell lymphoma, lymph nodes of head, face, and neck
	C83.02	Small cell B-cell lymphoma, intrathoracic lymph nodes
	C83.03	Small cell B-cell lymphoma, intra-abdominal lymph nodes
	C83.04	Small cell B-cell lymphoma, lymph nodes of axilla and upper limb
	C83.05	Small cell B-cell lymphoma, lymph nodes of inguinal region and lower limb
	C83.06	Small cell B-cell lymphoma, intrapelvic lymph nodes
	C83.07	Small cell B-cell lymphoma, spleen
	C83.08	Small cell B-cell lymphoma, lymph nodes of multiple sites
	C83.09	Small cell B-cell lymphoma, extranodal and solid organ sites
	C83.10	Mantle cell lymphoma, unspecified site
	C83.11	Mantle cell lymphoma, lymph nodes of head, face, and neck
	C83.12	Mantle cell lymphoma, intrathoracic lymph nodes
	C83.13	Mantle cell lymphoma, intra-abdominal lymph nodes
	C83.14	Mantle cell lymphoma, lymph nodes of axilla and upper limb
	C83.15	Mantle cell lymphoma, lymph nodes of inguinal region and lower limb
	C83.16	Mantle cell lymphoma, intrapelvic lymph nodes
	C83.17	Mantle cell lymphoma, spleen
	C83.18	Mantle cell lymphoma, lymph nodes of multiple sites
	C83.19	Mantle cell lymphoma, extranodal and solid organ sites
	C83.30	Diffuse large B-cell lymphoma, unspecified site
	C83.31	Diffuse large B-cell lymphoma, lymph nodes of head, face, and neck
	C83.32	Diffuse large B-cell lymphoma, intrathoracic lymph nodes
	C83.33	Diffuse large B-cell lymphoma, intra-abdominal lymph nodes
	C83.34	Diffuse large B-cell lymphoma, lymph nodes of axilla and upper limb
	C83.35	Diffuse large B-cell lymphoma, lymph nodes of inguinal region and lower limb
	C83.36	Diffuse large B-cell lymphoma, intrapelvic lymph nodes
	C83.37	Diffuse large B-cell lymphoma, spleen
	C83.38	Diffuse large B-cell lymphoma, lymph nodes of multiple sites
	C83.39	Diffuse large B-cell lymphoma, extranodal and solid organ sites
	C83.50	Lymphoblastic (diffuse) lymphoma, unspecified site
	C83.51	Lymphoblastic (diffuse) lymphoma, lymph nodes of head, face, and neck
	C83.52	Lymphoblastic (diffuse) lymphoma, intrathoracic lymph nodes
	C83.53	Lymphoblastic (diffuse) lymphoma, intra-abdominal lymph nodes
	C83.54	Lymphoblastic (diffuse) lymphoma, lymph nodes of axilla and upper limb
	C83.55	Lymphoblastic (diffuse) lymphoma, lymph nodes of inguinal region and lower limb
	C83.56	Lymphoblastic (diffuse) lymphoma, intrapelvic lymph nodes
	C83.57	Lymphoblastic (diffuse) lymphoma, spleen
	C83.58	Lymphoblastic (diffuse) lymphoma, lymph nodes of multiple sites
	C83.59	Lymphoblastic (diffuse) lymphoma, extranodal and solid organ sites
	C83.70	Burkitt lymphoma, unspecified site
	C83.71	Burkitt lymphoma, lymph nodes of head, face, and neck
	C83.72	Burkitt lymphoma, intrathoracic lymph nodes
	C83.73	Burkitt lymphoma, intra-abdominal lymph nodes
	C83.74	Burkitt lymphoma, lymph nodes of axilla and upper limb
	C83.75	Burkitt lymphoma, lymph nodes of inguinal region and lower limb
	C83.76	Burkitt lymphoma, intrapelvic lymph nodes
	C83.77	Burkitt lymphoma, spleen
	C83.78	Burkitt lymphoma, lymph nodes of multiple sites
	C83.79	Burkitt lymphoma, extranodal and solid organ sites
	C83.80	Other non-follicular lymphoma, unspecified site
	C83.81	Other non-follicular lymphoma, lymph nodes of head, face, and neck
	C83.82	Other non-follicular lymphoma, intrathoracic lymph nodes
	C83.83	Other non-follicular lymphoma, intra-abdominal lymph nodes
	C83.84	Other non-follicular lymphoma, lymph nodes of axilla and upper limb
	C83.85	Other non-follicular lymphoma, lymph nodes of inguinal region and lower limb
	C83.86	Other non-follicular lymphoma, intrapelvic lymph nodes
	C83.87	Other non-follicular lymphoma, spleen
	C83.88	Other non-follicular lymphoma, lymph nodes of multiple sites
	C83.89	Other non-follicular lymphoma, extranodal and solid organ sites
	C83.90	Non-follicular (diffuse) lymphoma, unspecified, unspecified site
	C83.91	Non-follicular (diffuse) lymphoma, unspecified, lymph nodes of head, face, and neck
	C83.92	Non-follicular (diffuse) lymphoma, unspecified, intrathoracic lymph nodes
	C83.93	Non-follicular (diffuse) lymphoma, unspecified, intra-abdominal lymph nodes
	C83.94	Non-follicular (diffuse) lymphoma, unspecified, lymph nodes of axilla and upper limb
	C83.95	Non-follicular (diffuse) lymphoma, unspecified, lymph nodes of inguinal region and lower limb
	C83.96	Non-follicular (diffuse) lymphoma, unspecified, intrapelvic lymph nodes
	C83.97	Non-follicular (diffuse) lymphoma, unspecified, spleen
	C83.98	Non-follicular (diffuse) lymphoma, unspecified, lymph nodes of multiple sites
	C83.99	Non-follicular (diffuse) lymphoma, unspecified, extranodal and solid organ sites
	C84.00	Mycosis fungoides, unspecified site
	C84.01	Mycosis fungoides, lymph nodes of head, face, and neck
	C84.02	Mycosis fungoides, intrathoracic lymph nodes
	C84.03	Mycosis fungoides, intra-abdominal lymph nodes
	C84.04	Mycosis fungoides, lymph nodes of axilla and upper limb
	C84.05	Mycosis fungoides, lymph nodes of inguinal region and lower limb
	C84.06	Mycosis fungoides, intrapelvic lymph nodes
	C84.07	Mycosis fungoides, spleen
	C84.08	Mycosis fungoides, lymph nodes of multiple sites
	C84.09	Mycosis fungoides, extranodal and solid organ sites
	C84.10	Sezary disease, unspecified site
	C84.11	Sezary disease, lymph nodes of head, face, and neck
	C84.12	Sezary disease, intrathoracic lymph nodes
	C84.13	Sezary disease, intra-abdominal lymph nodes
	C84.14	Sezary disease, lymph nodes of axilla and upper limb
	C84.15	Sezary disease, lymph nodes of inguinal region and lower limb
	C84.16	Sezary disease, intrapelvic lymph nodes
	C84.17	Sezary disease, spleen
	C84.18	Sezary disease, lymph nodes of multiple sites
	C84.19	Sezary disease, extranodal and solid organ sites
	C84.40	Peripheral T-cell lymphoma, not classified, unspecified site
	C84.41	Peripheral T-cell lymphoma, not classified, lymph nodes of head, face, and neck
	C84.42	Peripheral T-cell lymphoma, not classified, intrathoracic lymph nodes
	C84.43	Peripheral T-cell lymphoma, not classified, intra-abdominal lymph nodes
	C84.44	Peripheral T-cell lymphoma, not classified, lymph nodes of axilla and upper limb
	C84.45	Peripheral T-cell lymphoma, not classified, lymph nodes of inguinal region and lower limb
	C84.46	Peripheral T-cell lymphoma, not classified, intrapelvic lymph nodes
	C84.47	Peripheral T-cell lymphoma, not classified, spleen
	C84.48	Peripheral T-cell lymphoma, not classified, lymph nodes of multiple sites
	C84.49	Peripheral T-cell lymphoma, not classified, extranodal and solid organ sites
	C84.60	Anaplastic large cell lymphoma, ALK-positive, unspecified site
	C84.61	Anaplastic large cell lymphoma, ALK-positive, lymph nodes of head, face, and neck
	C84.62	Anaplastic large cell lymphoma, ALK-positive, intrathoracic lymph nodes
	C84.63	Anaplastic large cell lymphoma, ALK-positive, intra-abdominal lymph nodes
	C84.64	Anaplastic large cell lymphoma, ALK-positive, lymph nodes of axilla and upper limb
	C84.65	Anaplastic large cell lymphoma, ALK-positive, lymph nodes of inguinal region and lower limb
	C84.66	Anaplastic large cell lymphoma, ALK-positive, intrapelvic lymph nodes
	C84.67	Anaplastic large cell lymphoma, ALK-positive, spleen
	C84.68	Anaplastic large cell lymphoma, ALK-positive, lymph nodes of multiple sites
	C84.69	Anaplastic large cell lymphoma, ALK-positive, extranodal and solid organ sites
	C84.70	Anaplastic large cell lymphoma, ALK-negative, unspecified site
	C84.71	Anaplastic large cell lymphoma, ALK-negative, lymph nodes of head, face, and neck
	C84.72	Anaplastic large cell lymphoma, ALK-negative, intrathoracic lymph nodes
	C84.73	Anaplastic large cell lymphoma, ALK-negative, intra-abdominal lymph nodes
	C84.74	Anaplastic large cell lymphoma, ALK-negative, lymph nodes of axilla and upper limb
	C84.75	Anaplastic large cell lymphoma, ALK-negative, lymph nodes of inguinal region and lower limb
	C84.76	Anaplastic large cell lymphoma, ALK-negative, intrapelvic lymph nodes
	C84.77	Anaplastic large cell lymphoma, ALK-negative, spleen
	C84.78	Anaplastic large cell lymphoma, ALK-negative, lymph nodes of multiple sites
	C84.79	Anaplastic large cell lymphoma, ALK-negative, extranodal and solid organ sites
	C84.A0	Cutaneous T-cell lymphoma, unspecified, unspecified site
	C84.A1	Cutaneous T-cell lymphoma, unspecified lymph nodes of head, face, and neck
	C84.A2	Cutaneous T-cell lymphoma, unspecified, intrathoracic lymph nodes
	C84.A3	Cutaneous T-cell lymphoma, unspecified, intra-abdominal lymph nodes
	C84.A4	Cutaneous T-cell lymphoma, unspecified, lymph nodes of axilla and upper limb
	C84.A5	Cutaneous T-cell lymphoma, unspecified, lymph nodes of inguinal region and lower limb
	C84.A6	Cutaneous T-cell lymphoma, unspecified, intrapelvic lymph nodes
	C84.A7	Cutaneous T-cell lymphoma, unspecified, spleen
	C84.A8	Cutaneous T-cell lymphoma, unspecified, lymph nodes of multiple sites
	C84.A9	Cutaneous T-cell lymphoma, unspecified, extranodal and solid organ sites
	C84.Z0	Other mature T/NK-cell lymphomas, unspecified site
	C84.Z1	Other mature T/NK-cell lymphomas, lymph nodes of head, face, and neck
	C84.Z2	Other mature T/NK-cell lymphomas, intrathoracic lymph nodes
	C84.Z3	Other mature T/NK-cell lymphomas, intra-abdominal lymph nodes
	C84.Z4	Other mature T/NK-cell lymphomas, lymph nodes of axilla and upper limb
	C84.Z5	Other mature T/NK-cell lymphomas, lymph nodes of inguinal region and lower limb
	C84.Z6	Other mature T/NK-cell lymphomas, intrapelvic lymph nodes
	C84.Z7	Other mature T/NK-cell lymphomas, spleen
	C84.Z8	Other mature T/NK-cell lymphomas, lymph nodes of multiple sites
	C84.Z9	Other mature T/NK-cell lymphomas, extranodal and solid organ sites
	C84.90	Mature T/NK-cell lymphomas, unspecified, unspecified site
	C84.91	Mature T/NK-cell lymphomas, unspecified, lymph nodes of head, face, and neck
	C84.92	Mature T/NK-cell lymphomas, unspecified, intrathoracic lymph nodes
	C84.93	Mature T/NK-cell lymphomas, unspecified, intra-abdominal lymph nodes
	C84.94	Mature T/NK-cell lymphomas, unspecified, lymph nodes of axilla and upper limb
	C84.95	Mature T/NK-cell lymphomas, unspecified, lymph nodes of inguinal region and lower limb
	C84.96	Mature T/NK-cell lymphomas, unspecified, intrapelvic lymph nodes
	C84.97	Mature T/NK-cell lymphomas, unspecified, spleen
	C84.98	Mature T/NK-cell lymphomas, unspecified, lymph nodes of multiple sites
	C84.99	Mature T/NK-cell lymphomas, unspecified, extranodal and solid organ sites
	C85.10	Unspecified B-cell lymphoma, unspecified site
	C85.11	Unspecified B-cell lymphoma, lymph nodes of head, face, and neck
	C85.12	Unspecified B-cell lymphoma, intrathoracic lymph nodes
	C85.13	Unspecified B-cell lymphoma, intra-abdominal lymph nodes
	C85.14	Unspecified B-cell lymphoma, lymph nodes of axilla and upper limb
	C85.15	Unspecified B-cell lymphoma, lymph nodes of inguinal region and lower limb
	C85.16	Unspecified B-cell lymphoma, intrapelvic lymph nodes
	C85.17	Unspecified B-cell lymphoma, spleen
	C85.18	Unspecified B-cell lymphoma, lymph nodes of multiple sites
	C85.19	Unspecified B-cell lymphoma, extranodal and solid organ sites
	C85.20	Mediastinal (thymic) large B-cell lymphoma, unspecified site
	C85.21	Mediastinal (thymic) large B-cell lymphoma, lymph nodes of head, face, and neck
	C85.22	Mediastinal (thymic) large B-cell lymphoma, intrathoracic lymph nodes
	C85.23	Mediastinal (thymic) large B-cell lymphoma, intra-abdominal lymph nodes
	C85.24	Mediastinal (thymic) large B-cell lymphoma, lymph nodes of axilla and upper limb
	C85.25	Mediastinal (thymic) large B-cell lymphoma, lymph nodes of inguinal region and lower limb
	C85.26	Mediastinal (thymic) large B-cell lymphoma, intrapelvic lymph nodes
	C85.27	Mediastinal (thymic) large B-cell lymphoma, spleen
	C85.28	Mediastinal (thymic) large B-cell lymphoma, lymph nodes of multiple sites
	C85.29	Mediastinal (thymic) large B-cell lymphoma, extranodal and solid organ sites
	C85.80	Other specified types of non-Hodgkin lymphoma, unspecified site
	C85.81	Other specified types of non-Hodgkin lymphoma, lymph nodes of head, face, and neck
	C85.82	Other specified types of non-Hodgkin lymphoma, intrathoracic lymph nodes
	C85.83	Other specified types of non-Hodgkin lymphoma, intra-abdominal lymph nodes
	C85.84	Other specified types of non-Hodgkin lymphoma, lymph nodes of axilla and upper limb
	C85.85	Other specified types of non-Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
	C85.86	Other specified types of non-Hodgkin lymphoma, intrapelvic lymph nodes
	CODE	DESCRIPTION
	C85.87	Other specified types of non-Hodgkin lymphoma, spleen
	C85.88	Other specified types of non-Hodgkin lymphoma, lymph nodes of multiple sites
	C85.89	Other specified types of non-Hodgkin lymphoma, extranodal and solid organ sites
	C85.90	Non-Hodgkin lymphoma, unspecified, unspecified site
	C85.91	Non-Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck
	C85.92	Non-Hodgkin lymphoma, unspecified, intrathoracic lymph nodes
	C85.93	Non-Hodgkin lymphoma, unspecified, intra-abdominal lymph nodes
	C85.94	Non-Hodgkin lymphoma, unspecified, lymph nodes of axilla and upper limb
	C85.95	Non-Hodgkin lymphoma, unspecified, lymph nodes of inguinal region and lower limb
	C85.96	Non-Hodgkin lymphoma, unspecified, intrapelvic lymph nodes
	C85.97	Non-Hodgkin lymphoma, unspecified, spleen
	C85.98	Non-Hodgkin lymphoma, unspecified, lymph nodes of multiple sites
	C85.99	Non-Hodgkin lymphoma, unspecified, extranodal and solid organ sites
	C86.0	Extranodal NK/T-cell lymphoma, nasal type
	C86.1	Hepatosplenic T-cell lymphoma
	C86.2	Enteropathy-type (intestinal) T-cell lymphoma
	C86.3	Subcutaneous panniculitis-like T-cell lymphoma
	C86.4	Blastic NK-cell lymphoma
	C86.5	Angioimmunoblastic T-cell lymphoma
	C86.6	Primary cutaneous CD30-positive T-cell proliferations
	C88.0	Waldenstrom macroglobulinemia
	C88.2	Heavy chain disease
	C88.3	Immunoproliferative small intestinal disease
	C88.4	Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
	C88.8	Other malignant immunoproliferative diseases
	C88.9	Malignant immunoproliferative disease, unspecified
	C90.00	Multiple myeloma not having achieved remission
	C90.01	Multiple myeloma in remission
	C90.02	Multiple myeloma in relapse
	C90.10	Plasma cell leukemia not having achieved remission
	C90.11	Plasma cell leukemia in remission
	C90.12	Plasma cell leukemia in relapse
	C90.20	Extramedullary plasmacytoma not having achieved remission
	C90.21	Extramedullary plasmacytoma in remission
	C90.22	Extramedullary plasmacytoma in relapse
	C90.30	Solitary plasmacytoma not having achieved remission
	C90.31	Solitary plasmacytoma in remission
	C90.32	Solitary plasmacytoma in relapse
	C91.00	Acute lymphoblastic leukemia not having achieved remission
	C91.01	Acute lymphoblastic leukemia, in remission
	C91.02	Acute lymphoblastic leukemia, in relapse
	C91.10	Chronic lymphocytic leukemia of B-cell type not having achieved remission
	C91.11	Chronic lymphocytic leukemia of B-cell type in remission
	C91.12	Chronic lymphocytic leukemia of B-cell type in relapse
	C91.30	Prolymphocytic leukemia of B-cell type not having achieved remission
	C91.31	Prolymphocytic leukemia of B-cell type, in remission
	C91.32	Prolymphocytic leukemia of B-cell type, in relapse
	C91.40	Hairy cell leukemia not having achieved remission
	C91.41	Hairy cell leukemia, in remission
	C91.42	Hairy cell leukemia, in relapse
	C91.50	Adult T-cell lymphoma/leukemia (HTLV-1-associated) not having achieved remission
	C91.51	Adult T-cell lymphoma/leukemia (HTLV-1-associated), in remission
	C91.52	Adult T-cell lymphoma/leukemia (HTLV-1-associated), in relapse
	C91.60	Prolymphocytic leukemia of T-cell type not having achieved remission
	C91.61	Prolymphocytic leukemia of T-cell type, in remission
	C91.62	Prolymphocytic leukemia of T-cell type, in relapse
	C91.A0	Mature B-cell leukemia Burkitt-type not having achieved remission
	C91.A1	Mature B-cell leukemia Burkitt-type, in remission
	C91.A2	Mature B-cell leukemia Burkitt-type, in relapse
	C91.Z0	Other lymphoid leukemia not having achieved remission
	C91.Z1	Other lymphoid leukemia, in remission
	C91.Z2	Other lymphoid leukemia, in relapse
	C96.0	Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis
	C96.20	Malignant mast cell neoplasm, unspecified
	C96.21	Aggressive systemic mastocytosis
	C96.22	Mast cell sarcoma
	C96.29	Other malignant mast cell neoplasm
	C96.A	Histiocytic sarcoma
	D03.0	Melanoma in situ of lip
	D03.10	Melanoma in situ of unspecified eyelid, including canthus
	D03.111	Melanoma in situ of right upper eyelid, including canthus
	D03.112	Melanoma in situ of right lower eyelid, including canthus
	D03.121	Melanoma in situ of left upper eyelid, including canthus
	D03.122	Melanoma in situ of left lower eyelid, including canthus
	D03.20	Melanoma in situ of unspecified ear and external auricular canal
	D03.21	Melanoma in situ of right ear and external auricular canal
	D03.22	Melanoma in situ of left ear and external auricular canal
	D03.30	Melanoma in situ of unspecified part of face
	D03.39	Melanoma in situ of other parts of face
	D03.4	Melanoma in situ of scalp and neck
	D03.51	Melanoma in situ of anal skin
	D03.52	Melanoma in situ of breast (skin) (soft tissue)
	D03.59	Melanoma in situ of other part of trunk
	D03.60	Melanoma in situ of unspecified upper limb, including shoulder
	D03.61	Melanoma in situ of right upper limb, including shoulder
	D03.62	Melanoma in situ of left upper limb, including shoulder
	D03.70	Melanoma in situ of unspecified lower limb, including hip
	D03.71	Melanoma in situ of right lower limb, including hip
	D03.72	Melanoma in situ of left lower limb, including hip
	D03.8	Melanoma in situ of other sites
	D03.9	Melanoma in situ, unspecified
Primary Diagnosis	Code	Description
	D46.0	Refractory anemia without ring sideroblasts, so stated
	D46.1	Refractory anemia with ring sideroblasts
	D46.20	Refractory anemia with excess of blasts, unspecified
	D46.21	Refractory anemia with excess of blasts 1
	D46.22	Refractory anemia with excess of blasts 2
	D46.A	Refractory cytopenia with multilineage dysplasia
	D46.B	Refractory cytopenia with multilineage dysplasia and ring sideroblasts
	D46.C	Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
	D46.4	Refractory anemia, unspecified
	D46.Z	Other myelodysplastic syndromes
	D46.9	Myelodysplastic syndrome, unspecified
	D47.Z1	Post-transplant lymphoproliferative disorder (PTLD)
	D70.0	Congenital agranulocytosis
	D70.1	Agranulocytosis secondary to cancer chemotherapy
	D70.2	Other drug-induced agranulocytosis
	D70.3	Neutropenia due to infection
	D70.4	Cyclic neutropenia
	D70.8	Other neutropenia
	D70.9	Neutropenia, unspecified
	T45.1X5A	Adverse effect of antineoplastic and immunosuppressive drugs, initial encounter
	T45.1X5D	Adverse effect of antineoplastic and immunosuppressive drugs, subsequent encounter
	T45.1X5S	Adverse effect of antineoplastic and immunosuppressive drugs, sequela
	T50.905A	Adverse effect of unspecified drugs, medicaments and biological substances, initial encounter
	T50.905D	Adverse effect of unspecified drugs, medicaments and biological substances, subsequent encounter
	T50.905S	Adverse effect of unspecified drugs, medicaments and biological substances, sequela
	T50.995A	Adverse effect of other drugs, medicaments and biological substances, initial encounter
	T50.995D	Adverse effect of other drugs, medicaments and biological substances, subsequent encounter
	T50.995S	Adverse effect of other drugs, medicaments and biological substances, sequela
Encounter Status Code set	Code	Description
	Z41.8	Encounter for other procedures for purposes other than remedying health state
	Z48.288	Encounter for aftercare following multiple organ transplant
	Z48.290*	Encounter for aftercare following bone marrow transplant
	Z51.11	Encounter for antineoplastic chemotherapy
	Z51.89	Encounter for other specified aftercare
	Z52.89	Donor of other specified organs or tissues
	Z79.899*	Other long term (current) drug therapy
	Z94.81*	Bone marrow transplant status
	Z94.84*	Stem cells transplant status
	Z94.9	Transplanted organ and tissue status, unspecified
Group 1 Medical Necessity ICD-10-CM Codes Asterisk Explanation * Diagnosis code Z79.899 should not be billed as the primary diagnosis. For Z48.290, Z94.81 or Z94.84 the underlying condition should be billed as the primary diagnosis code.

Applicable Modifiers

Policy History

Date	Action	Description
5/10/2024	Policy Review. LCD references updated	Policy was review for clinical criteria and FDA approved indications per approved agents. LCD references were removed from policy due CMS contractor retirted the applicable LCD. Policy presented at the Utilization Management committee
10/26/2023	Policy Review	Reviewed by the Providers Advisory Committee. No change.
10/10/2023	Replace Policy	Policy M5.001.006 merged with policy M5.001.004.
9/25/2023	Preferred agent determination	Due to limitations in market availability of Ziextenzo it was removed as a preferred agent. CSF-LA products: Neulasta, Neulasta OnPro to be removed as preferred agents effective 10/01/2023.
12/29/2022	Preferred agent determination	Zarxio defined as preferred product for all population that comply with medical necessity criteria. Removed language referred to naive individuals.
11/09/2022	Annual Review	Reviewed by the Providers Advisory Committee. No changes
11/10/2021	Annual Review	Reviewed by the Providers Advisory Committee. No changes
9/01/2021	New Policy	Preferred products determination for G-CSF Filgrastim and Pegfilgrastim

CSF Hematopoietic Colony Stimulating Factors

Codes

Number

Description